Histopathological Study in Alloxan-Induced Diabetic Mice Treated With Tapinanthus globiferus Flowers Extract

Mofeed Al- Nowihi^1*, Maher Al-Absi², Abdu Faisal², Fatima Al-Futaini¹ & Gawed Al- Asbhai

¹Department of Biology, Histology and Cytology, Faculty of Science, Sana’a University, Yemen
²Faculty of Pharmacy, Sana’a University, Yemen

Dr. Mofeed Al- Nowihi, Department of Biology, Histology and Cytology, Faculty of Science, Sana’a University, Yemen.

Keywords: Tapinanthus globiferus; Histopathology; Alloxan Induce; Hyperglycemia; Pancreatic Tissue

Abstract

Objectives
The aim of this study is to investigate the capacity of flower extracts of Tapinanthus globiferus to reverse pancreatic injuries in alloxan-induced hyperglycemic mice.
Introduction
Diabetes mellitus (DM) is a chronic metabolic disorder, which affects over 150 million people in the world today, and this will be doubled by 2025. DM is considered the sixth leading cause of death globally.
Design of Experiment
A total of 36 male Wistar albino mice allotted into six groups of six mice each. They were kept in standard environmental conditions for one week and fed formulated mice food and water.

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