Role of Microbes and its Interaction with Innate Lymphoid System

Mukesh Verma^* & Ajay Kumar Singh^*

Department of Medicine, National Jewish Health, 1400 Jackson St., Denver, Colorado, USA

Mukesh Verma & Dr. Ajay Kumar Singh, Department of Medicine, National Jewish Health, 1400 Jackson St., Denver, Colorado, USA.

Keywords: Microbes; Innate Lymphoid Cells (ILCs); Pattern Recognition Receptors (PRRs)

Abstract

In-depth research of ILC family in immunity panel is growing rapidly. Many studies have been done to know the specific ILCs function in different sites triggering immunity, tissue repair and inflammation. Therefore, microbial interaction with ILC group which play specific roles in host homeostasis is not fully understand. A very few studies have been done in the ILC1 and ILC3 with microbial interaction but not with the ILC2s. However, ILCs have elucidated research interests in the fields of infectious immunity, inflammatory diseases, and allergic diseases. In this review we are focusing about the ILCs and how microbes interact with innate lymphocytes.

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