Mechanotransduction; Comparing Four Mechanical Forces

Osama S. Abbadi^1* & Ayoub A. Mohamed²

¹Department of Biochemistry, Faculty of Medicine, Omdurman Islamic University, Sudan
²Department of Medicine, Section of Infectious Diseases, King Abdulaziz Medical City, Riyadh, Saudi

Dr. Osama S. Abbadi, Department of Biochemistry, Faculty of Medicine, Omdurman Islamic University, Sudan.

Keywords: Mechanotransduction; Stretch Force; Fluid Flow; Fluid Pressure

Abstract

Physical forces affect homeostasis. The recent advances in molecular techniques and tissue assays allowed the science to measure these effects at the level of proteins, growth factors, and gene expression. In this short review, we report the experimental work done by molecular biologists with regard to the molecular changes in response to four different types of physical stimuli: stretch, fluid flow, fluid pressure, and negative pressure.

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