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In this mini-review the developments in curcumin nanoformulations as part of food nanotechnology in general are discussed with a special emphasis on the application of curcumin nanoformulations in oncology. Although these nanoformulations overcome poor curcumin bioavailability, there is no evidence for a significant role of curcumin in oncology until now, despite thousands of studies. Long-term toxicity of nanoformulations in food technology and biopharma is not known at all. Therefore, an inter [..] READ MORE
COPD is a complex inflammatory disorder that leads to the destruction of lung tissue and compromises the pulmonary function. The process involves innate and adaptive immunity, and is regulated by inflammatory cells infiltrated, which through the production of cytokines and chemokines perpetuate and exacerbate the inflammation. [..] READ MORE
Renal ischemia/reperfusion injury (IRI) is the major cause of acute kidney injury (AKI) in native and transplanted kidneys, with a complex pathogenesis involving leukocyte infiltration, and release of proinflammatory mediators by tubular cells. Recent evidences have shown a critical role of the CD4+ T cells, and the balance between Th1/Th2 cells as possible effector mechanism. In order to evaluate the role of Th1/Th2 immune response in this system, IL-4, IL-10, IL-12 deficient mice an [..] READ MORE
A case of radiation-induced occlusion of both internal carotid arteries is presented. A 58-year-old man with history of surgical treatment for oropharyneal carcinoma followed by radiotherapy 5 years ago, presented with a right-sided fronto-temporo-parietal infarction as a result of insufficient cerebral blood supply. Angiography revealed occlusion of both internal carotid arteries and a right-sided occlusion of common carotid artery. We describe an unusually efficient reorganization of his cereb [..] READ MORE
Vestigial organs are the troubled side of human life because occasionally we are affected some ailments like appendicitis and tonsillitis which may fatal for our life. Conversely, these diseases were very common in our ancestor. In fact, the word ‘Evolution’ is the most live word and controversially a rational matter to pick-up the evidences on vestigial organs of human body. Applying the theory of Lamarck and Darwin, the medical science department may run speedy for human welfare. In this regar [..] READ MORE
Background
In nursing practice in common with other professional disciplines the generation of new questions to inform research is the foundation of the development of new knowledge. [..] READ MORE
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