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Volume 3 Issue 5
Novel Hyperkalemia Drugs
In this mini-review pathophysiology, diagnosis and management of hyperkalemia are discussed with a special emphasis on the introduction of two novel potassium binders, patiromer and sodium zirconium cyclosilicate. These novel potassium binders enable patients to continue RAASi therapy in CHF, diabetes and CKD. Both have tested well as safe and efficacious and may result in a change in our therapeutic paradigm, by favouring their chronic use over discontinuation of RAASi treatment. Whether the ef [..] READ MORE
Stress Urinary Incontinence in Crossfit Practicing Women in Macapá, A Northern City of Brazil
The Urinary incontinence (UI) is defined as the complaint of involuntary urine loss, a common clinical situation among women that can occur at any age group. The emergence UI has been associated with the practice of strenuous physical exercises. Among these activities there is the CrossFit. However, there are still few studies calculating the prevalence of urinary incontinence in the practitioners of this physical activity. In that way, this study is essential, since the UI considerably impairs [..] READ MORE
Shared Voices of the Survivors’ Journey in Coping with Trauma after the Worlds’ Strongest Thypoon Haiyan: Suffering, Caring and Faith
There have been a variety of natural disasters experienced worldwide. Some of them have really made history because of their devastating, long-lasting effects. Natural disasters will continue to occur, and most of them occur with little to no warning. People affected by disasters had shown difficulty in coping with these occurrences. Government interventions focused more on the rebuilding efforts but lesser emphasis has been made to focus on people’s means of coping.
The earthquake that hit J [..] READ MORE
Hepatopulmonary Syndrome: Could Contrast Transesophageal Echocardiography be the Gold Standard for Diagnosis?
Hepatopulmonary syndrome (HPS) is a clinical relationship between liver disease and intrapulmonary vasodilatations that may result in hypoxemia. HPS may be diagnosed using transthoracic echocardiography (TTE), currently considered the gold standard, or transesophageal echocardiography (TEE) having been described to present greater sensitivity for the detection of bubbles (contrast). The aim of this study was to determine the prevalence of HPS and evaluate the role of contrast TEE in defining dia [..] READ MORE
Thrombocytopenia in Chronic Liver Disease; New Developments
In this mini-review pathophysiology of thrombocytopenia in chronic liver disease (CLD) are discussed with a special emphasises on novel drug therapeutics. Two, recently approved thrombopoietin (TPO) mimetics, lusutrombopag and avatrombopag, provide clinicians a safe and effective alternative to platelet transfusions in CLD patients with thrombocytopenia who are scheduled for an elective invasive procedure. Both TPO mimetics reduced the need for platelet transfusions significantly. [..] READ MORE
Albuminuria in Saudi Patients with Type 2 Diabetes and Hypertension
Background and Objective
Albuminuria is a risk factor for cardiovascular disease, and excess urinary albumin is related to increased all-cause mortality. Patients with type 2 diabetes (T2DM) are almost twice as likely to have hypertension (HTN) as the nondiabetic population. There have been few reported studies in national, regional and Asian populations on the prevalence of microalbuminuria in this high risk population. [..] READ MORE
Total Articles Published
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