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Volume 1 Issue 3
Why Mothers are not Responsible for Down Syndrome Children?
Basing on my published article titled : Nondisjunction (extra chromosome 21(T21) and Down Syndrome (DS)) is not a maternal cause. It is a parental issue. An appeal to all mothers throughout the world [1]. I want to remind you that, Since the wrong proposal of Calvin Bridge and Thomas Hunt Morgan in the spring of 1910 for the so called (non-disjunction), as an origin of Trisomy21 and Down syndrome, a hot controversy had been raised. No scientific ideas or hypotheses were proposed exactly, to put [..] READ MORE
Local Breast Cancer Treatment based on Targeted Oncoplastic Breast Surgery (TOBS) and Breast Imaging
Preoperative staging of breast cancer based on breast imaging (mammography, breast sonography and breast magnetic resonance tomography (MR-mammography)) is mandatory. Earlier diagnosis of breast cancer leads more likely to favourable oncological outcome. Histological results of different Interventional procedures guided by ultrasound, stereotactic mammography or magnetic resonance in sense of image-guided wire markings are the basis for planning surgical resection margins in oncoplastic breast-c [..] READ MORE
Prostate Cancer Management by Hormone Therapy May Increase the Risk of Neurological and Cardiac Disorders
The prostate is a gland in the male reproductive system that cause the production of fluid that forms the semen, the sperms are carried by this thick fluid.
With the advancement of men age, the prostate approximately unavoidably grows larger. [..] READ MORE
Histone Post-Translational Modifications and Cancer
Epigenetic involves mechanisms which control gene transcription but convey no changes in the DNA sequences. A series of epigenetic modifications have been described in several tumors and this knowledge is important for the adequate diagnosis and treatment of the disease. [..] READ MORE
Genes Profiling of a Patient with Chronic Myeloid Leukemia on Illumina MiSeq Platform: A Cases Report
CML is a malignant disease of the pluripotent hematopoietic stem cell characterized by the Philadelphia chromosome (Ph) and a rearrangement between the BCR gene (break-point cluster region) and the ABL gene. Albeit multiple advances of research in this field, the molecular mechanisms leading to establishment and development of this disease are not completely understood. The incidence of CML is influenced by different parameters like: demography, gender, ethnicity and socio-economic difference. [..] READ MORE
Virtosome: Is it the Answer to Liquid Biopsy Dilemma?
Liquid biopsy including circulating tumor cells (CTC), circulating tumor DNA (ct DNA) and exosomes and has been an attractive concept to both researchers and clinicians due to its convenience, dynamicity, universality, and cost-effectiveness. However, when it comes to real life application, it was faced by so many challenges that delayed taking this practice to a more widespread scale and involving it in cancer guidelines. Perhaps one of the most important points made was that the controversial [..] READ MORE
Total Articles Published
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